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MCHR1 antagonist 2
CAS No. 863115-70-2
MCHR1 antagonist 2( —— )
Catalog No. M26291 CAS No. 863115-70-2
MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 282 | Get Quote |
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| 10MG | 417 | Get Quote |
|
| 25MG | 683 | Get Quote |
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| 50MG | 963 | Get Quote |
|
| 100MG | 1287 | Get Quote |
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| 500MG | 2592 | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMCHR1 antagonist 2
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NoteResearch use only, not for human use.
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Brief DescriptionMCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG.
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DescriptionMCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG.(In Vitro):In IMR-32 cells, MCHR1 antagonist 2 shows inhibitory effects on Ca2+?flux, and hERG, with IC50s of 196?±?30 nM and 4.0?±?0.8 nM, respectively.
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In VitroMCHR1 antagonist 2 (Compound 30) is an antagonist of melanin concentrating hormone receptor 1, with an IC50 of 65 nM. MCHR1 antagonist 2 has inhibitory effects on Ca2+?flux, and hERG, with IC50s of 196?±?30 nM and 4.0?±?0.8 nM, respectively, in IMR-32 cells.
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetHER/HSP
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RecptorAPC
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Research Area——
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Indication——
Chemical Information
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CAS Number863115-70-2
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Formula Weight424.428
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Molecular FormulaC23H21FN2O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 10 mg/mL (23.56 mMul)
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SMILESFc1ccc2oc(cc(=O)c2c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Bai R L, Pettit G R, Hamel E. Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites. Journal of Biological Chemistry, 1990, 265(28): 17141-17149.
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